Ibuprofen use may be linked to male infertility

Ibuprofen use may be linked to male infertility

The study did not examine sperm production, so researchers say additional studies are necessary.

Now, one of those disruptors has come to light.

Also, the study indicated that men who are used to over-the-counter drugs to relieve minor aches could be at a higher risk of suffering even more serious health problems.

"Our immediate concern is for the fertility of men who use these drugs for a long time", said the University of Copenhagan's David Mobjerg Kristensen.

"These compounds are good painkillers, but a certain amount of people in society use them without thinking of them as proper medicines".

The more ibuprofen the subjects took, the bigger the negative effect the researchers found.

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The experiment involved 31 men under 35 in Denmark and France who were split into two groups, with the first taking 1,200 milligrams of ibuprofen each day for six weeks and the other a placebo.

Young men taking ibuprofen saw a coordination between luteinizing hormones (LH) - those that produce testosterone - and the level of ibuprofen in their bloodstream.

This is the maximum limit as directed by the labels of generic ibuprofen products.

The men's testosterone levels, however, didn't change, which leads to the condition of compensated hypogonadism. The results aren't yet clear. Bernard Jégou, of the French National Institutes of Health and Medical Research, and his co-authors wrote that ibuprofen appears to "affect the hormonal balance in adult men" and "alters human testicular physiology" - creating a situation where the body has to work harder to maintain some degree of normal testosterone.

But given how athletes routinely use the medication to help with recurring sports injuries, experts say this is something we definitely need to stay aware of - because despite how some might abuse it, ibuprofen isn't something that was ever meant to be taken casually.

The findings are reported in Proceedings of the National Academy of Sciences.


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