Polycystic Ovary Syndrome Cause Discovered And Scientists Believe They Have A Cure

Pregnancy

Now, scientists from the French National Institute of Health and Medical Research have discovered that PCOS may be triggered in the womb before birth - and they've found success with a potential cure.

We already know that the condition happens because of elevated levels androgens (male hormones) in females. Millions of women all over the world are affected by the condition, and researchers may have finally found the cause and treatment for it.

Calling it a new method for approaching PCOS, researchers said they hope to begin drug trials by the end of this year.

He told the New Scientist: 'It's by far the most common hormonal condition affecting women of reproductive age but it hasn't received a lot of attention. The researchers dosed pregnant mice with high levels of AMH, and found it caused them to have symptoms of PCOS including irregular menstruation, fertility issues, and late puberty.

Signs and symptoms include irregular or no menstrual periods, excess body and facial hair.

To do so, they injected AMH into pregnant mice. As their female offspring grew up, they displayed numerous hallmarks of polycystic ovary syndrome, including later puberty, infrequent ovulation, delays in falling pregnant, and fewer offspring.

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More than half of the women affected don't have any symptoms.

As the mice's female offspring aged they showed signs of polycystic ovary syndrome, suggesting the hormone could be a cause.

"It's a radical new way of thinking about polycystic ovary syndrome and opens up a whole range of opportunities for further investigation", says Norman. In this condition, the ovary or ovaries develop multiple fluid-filled sacs that contain immature eggs that do not mature for ovulation. According to the study, the extra AMH seemed to prompt overstimulation of a certain set of brain calls called GnRH neutrons, which control the body's testosterone levels.

Researchers were actually able to reverse this effect using an IVF drug called cetrorelix, and the mice ceased to have symptoms.

Levels of the hormone are known to decline as women get older. After treatment with this drug, the mice stopped showing symptoms of polycystic ovary syndrome.

PCOS sufferers should have a healthy diet, including at least five portions of fruit and vegetables a day, lean meat and fish, and dairy products, while avoiding anything too fatty or sugary.

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