HIV vaccine shows promise in human trialNaija247news

An estimated 37 million people live with HIV  AIDS according to the World Health Organization

Scientists will now carry out a trial named "Imbokodo", the Zulu word for rock, on 2,600 women in southern Africa.

Study leader Dan Barouch, a Harvard Medical School professor said that the results till now are "promising" but it is best to be "cautious".

In addition to being well-tolerated by all the test subjects and inducing an immune response against HIV in humans, the vaccine provided 67% protection against infection from the simian-human immunodeficiency virus in the rhesus monkeys. "We eagerly await the results of the phase 2b efficacy trial".

Only one so far, RV144, yielded some protection. "But the data is promising and we are happy to report the immune response".

The trial recruited 393 healthy, HIV-uninfected adults (aged 18-50 years) from 12 clinics in east Africa, South Africa, Thailand, and the US. They received 4 vaccinations through a period of forty-eight weeks.

In the APPROACH trial of almost 400 participants, researchers conducted a multicenter, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, and immunogenicity of several vaccine regimens in humans.

Previous HIV-1 vaccine candidates have typically been limited to specific regions of the world.

And although we now live in the era of PrEP - a highly effective, preventative drug - its high price tag makes it out of reach for numerous millions affected.

Until now, all the positive results show that researchers can continue testing it.

Fans get First Look at Hailey Baldwin's Engagement Ring from Justin Bieber
Baldwin was recently linked with singer Shawn Mendes after the pair attended the Met Gala in NY together in May. That's right, the Ontario native has apparently popped the question to his model girlfriend Hailey Baldwin .

Some of the volunteers reported some side effects but the researchers said they were tolerable. The findings showed the vaccines induced robust and comparable immune responses in humans and monkeys and protected monkeys against acquisition of infection.

We can not say anything on a note as the majority of studies which are done on the animals prove to be wrong when seen in humans.

"This one is novel in many ways, so it is exciting, but we have a long way to go".

Other researchers caution seeing this vaccine as the final solution to the virus.

With 1.8 million new cases of human immunodeficiency virus every year, according to United Nations estimates, and nearly 37 million people living with HIV worldwide, the quest for a vaccine has been urgent - and extremely hard. Worldwide, that number is even more daunting: About 1.8 million people are thought to have been infected in 2016.

About 35 million have died. The virus is able to mutate to avoid the attack of the human immune system, so we can't develop immunity to it.

Barouch disclosed support from the NIH, the Bill & Melinda Gates Foundation, and Janssen Vaccines & Prevention BV, and is a co-inventor on HIV-1 vaccine antigen patents that have been licensed to Janssen Vaccines & Prevention BV.

Dr Brady added that in the meantime there were already tools that were effective for preventing the disease from spreading, such as contraception and treatments for HIV-positive people that prevent them from passing on the virus.

Related:

Comments

Latest news

Lebanese tourist sentenced to 8 years' jail for Facebook post against Egypt
The 24-year-old was charged with "deliberately broadcasting false rumours which aim to undermine society and attack religions". The users decried the sentence as "excessively harsh" and some called for Lebanese to boycott tourist hotspots in Egypt .

Iran says Trump 'destabilising' oil market
He added that his refinery had cancelled USA crude imports and would switch to Middle East or West African supplies instead. At the same time, the United States president has been exerting pressure on his European allies to stop buying Iranian oil.

Erdogan vows to advance Turkey under new governance system
The opposition described Monday as the day when a partisan one-man regime officially starts ruling Turkey. The AKP lost its single-party parliamentray majority in the 24 June elections, winning 295 seats.

Deal Alert: Get 4 months of Amazon Music for only $0.99
Keep in mind that after the 4-month deal, the subscription will revert to full price, so you'll have to pay $9.99 each month. Prime Day deals will be identified by a badge, which reads "Prime Day deal" on a blue background.

Dick Cheney Signs Waterboarding Kit For Sacha Baron Cohen's New Show
Not only that, but he gets Cheney to sign a "waterboarding kit" in the clip for the series, which premieres on July 15th. Behind the elaborate setup is a genuine quest for the truth about people, places and politics.

Ethiopia and Eritrea restore ties after 20 years of enmity
He said the Ethiopian leader's visit was "history in the making" and had "set the tone for rapid, positive changes". He has pardoned dissidents, lifted a state of emergency and pledged to partly privatize key state-owned firms.

Trump Administration Freezes Payments to Affordable Care Act Insurers with Sicker Patients
Still, insurers are grappling with changes that the Trump administration and Congress have made to Obamacare for 2019. The move brought a sharp response from health insurers warning of market disruptions and higher costs.

Starbucks: No more plastic straws
The recyclable lids are already in use in about 8,000 Starbucks locations in the United States and Canada , the company said. The move will eliminate more than one billion plastic straws per year from Starbucks stores, the company said.

Meet Prince Louis's New Godparents
Both the Queen and the Duke of Edinburgh are to miss Prince Louis' christening later today, Buckingham Palace has confirmed . Proud parents the Duke and Duchess of Cambridge made their way into the service in London with their three children.

Harvey Weinstein Pleads Not Guilty to Additional Sexual Assault Charges
Weinstein's CT home for the past 23 years, she said, should no longer an option because records show that it has been sold. Courthouse guards told people arriving for jury duty to wait or use a different entrance as Weinstein arrived on Monday.

At Least One Dead After Helicopter Crashes Into Townhouses, Causing Massive Fire
Authorities are responding to an aviation crash, possibly involving a helicopter, in a residential area in Virginia. The crash happened near the College of William and Mary Dillard Complex, prompting an alert from the university.

Oprah‚ Beyoncé‚ Jay-Z headed to SA for Global Citizen Festival
There will also be opportunities for Global Citizens to earn free tickets by taking actions in their communities of Johannesburg. Local fans are losing their mind as they scramble for tickets but attendees have been informed that tickets are free of cost.

Xiaomi gets off to a slow start with Hong Kong IPO
Founded in 2010, Xiaomi was the fifth biggest smartphone maker in the world past year , according to research firm IDC. Mo Jia, a Shanghai-based analyst with industry consultancy Canalys, said the weak debut was to be expected.

Phil Thompson urges Liverpool to sign Harry Maguire
Thompson, who has been impressed by Maguire, was full of praise for the Leicester man. He's also very comfortable on the ball. But I think he would be worth it.

Phil Mickelson forced to take two-stroke penalty at Greenbrier
Mickelson took a double-bogey 6 for the hole on a day when he also had a triple-bogey 6 (on 18), three bogeys and four birdies. Almost a month after appalling the golf world (and violating the PGA rulebook) by putting a moving ball at the U.S.

Other news