Liverpool emerged as 3-2 victors but in his second appearance since the Champions League final - when his two mistakes cost Jurgen Klopp's side - Karius made a very large error.
The mistake prone German spilled a free-kick for Tranmere scored a tap in, and underlined the fact Liverpool just can not rely on him heading into the 2018/19 season.
The goalkeeper's latest gaffe came on his second appearance since being at fault for his side's infamous Champions League final defeat last season.
When Liverpool beat Roma to earn a place in Kiev, Tollitt tweeted: "GET IN THERE!"
Klopp defended Karius over the error after the game.
Eight boys now rescued from flooded cave in Thailand
Divers guided them though more than two miles of dark and narrow tunnels filled with murky water and strong currents. It took nine hours Sunday to rescue the first two boys, who were described as the weakest of the group.
He said: "No one likes that goal but, if we talk about that, then the second goal is Milly's [James Milner's] fault".
Speaking to Liverpool FC's website, Klopp said: "I'm not sure if I should have expected something different but it [the reception from fans] was nice, absolutely nice".
"You (the media) can all stop it immediately - promise?"
Does Jurgen Klopp need to make a move in the transfer window to replace Karius or should he continue to put his faith in the German? Our job is to support Loris, that's our part of the deal. I've seen this situation 500 times at least in my life - bam, against the chest, going down.
Karius also made a highly publicised error in the warm-up to the game against Chester at the weekend.
Liverpool have been dragging their heels over signing a new goalkeeper, with top targets Jan Oblak and Alisson regarded as too expensive.
I've engraved the Queen's head on a blob of gold and The Last Supper but I'm really proud of my portrait of Harry Kane . They worked in '98 and we worked today, we reached out target to get to the final.
It's wonderful because I was one of those kids growing up who wanted to play for England. "I would just walk out of the room, it is an anthem and has followed the team for a long time but involved some hard moments as well".
Earlier today, both Caroline and Andrew confirmed that they are no longer together and made sure to wish each other all the best. Caroline Flack has announced that her engagement to Andrew Brady is over in an emotional statement confirming their split.
Next year's Northern Trust will return to Liberty National in Jersey City, New Jersey, before heading to TPC Boston in 2020. Key to the changes was the PGA Championship moving from August to May, and The Players Championship returning to March.
I feel dumb saying hello to them and then saying hello again 10 minutes later, ' he said. "But look at what's going on out there". The host then explained how he never greets guests before the show because he prefers to do so on camera, which makes sense.
Novelist Shamsie, author of Home Fire , selected the Second World War classic from all of the winners of the 1990s. The victor was revealed at the Man Booker 50 Festival in London's Royal Festival Hall on Sunday.
Hours later, Erdogan announced the make-up a new streamlined cabinet which included his son-in-law as finance minister. The role of prime minister has also been eliminated, and the president will now be able to pick his own Cabinet.
The drama in Thailand has even resonated as far as Russian Federation , where soccer's World Cup is reaching its final stages. Despite all the risks associated with the rescue, she says she never had any doubt that the boys would all make it out.
The 21-year-old spent the second half of last season on loan at NAC Breda in the Eredivisie, in which he netted five goals. Having broken into Roma's squad aged just 18, he's also scored twice for them in six senior appearances.
The scandal took place before new European Union data protection laws that allow much larger fines came into force. That's despite earlier estimates that 2.7 million users in the European Union had their data improperly shared.
JetBlue flight crew credited with saving life of French bulldog
These flight attendants are being hailed for looking after their passengers - no matter their species - during their time of need. They placed a breathing mask over Darcy's nose and mouth and, thankfully, she responded to the extra oxygen nearly immediately.
George Clooney reportedly hurt in Italian scooter crash
A photo tweeted by the local news outlet shows a motorcycle beside a slightly damaged Mercedes and a fire extinguisher. The couple have also been joined by George's parents, Nina and Nick Clooney, and Amal's mother Baria Alamuddin.
Reuters Journalists Charged in Myanmar
They are charged with violating Section 3  [c] of the colonial-era law, which carries a maximum penalty of 14 years in prison. Yet the arrest failed to quash their story, which Reuters eventually published as a special report in February.
Prince Louis' Godparents Revealed - See the Full List!
Princess Charlotte took centre stage at her little brother Prince Louis's christening yesterday as she showed off her cheeky side. Coincidentally, William and Kate attended the wedding of Robert and Hannah on their own one-year wedding anniversary in 2012.
Emma Stone Stars In 'The Favourite' Trailer
The Crown's Olivia Coleman plays the role of Queen Anne with her advisor Lady Sarah played by Rachel Weisz . The cast includes Nicholas Hoult , Joe Alwyn , Mark Gatiss , Jenny Rainsford , and James Smith .
Mobile phone warning road signs 'a UK first'
A roadside system that detects if a mobile phone is in use in a passing vehicle is being piloted in a United Kingdom first. People using their phones while driving will be getting warning messages if they do so in Norfolk.
Queen pays tribute to mark 100 years of Royal Air Force
With three royal engagements in a single day, it's no wonder Meghan Markle has made an equal amount of outfit swaps. Meetings with The President of Ireland, Michael Higgins, and with The Taoiseach, Leo Varadkar, are both planned.
Eden Hazard still 'dreaming' of Real Madrid
But despite Zidane having been replaced by Julen Lopetegui, Hazard told beIN SPORTS his thinking had not really changed. If Real Madrid do indeed want to sign Hazard , they will certainly have to shell out staggering sums of money to do so.
Key numbers: Ronaldo to leave Madrid for Juventus
I'm leaving but this shirt, this shield and the Santiago Bernabéu will continue to always feel as my own wherever I am. He spent six seasons in England, winning three Premier League titles, one Champions League title and one FA Cup.