The appeal by Meng's wife for justice and fairness echoed pleas from the families of scores of people who fell afoul of the Chinese Communist Party under President Xi Jinping's rule.
Willy Lam, a Chinese politics expert at the Chinese University of Hong Kong, said Meng's case shows how Chinese officials, no matter where they are, have to obey the Communist Party first and foremost.
In a separate development, Interpol said it had received Meng's resignation from the global police agency with "immediate effect", according to statement posted on Sunday.
Hongwei, who went missing last month, is China's vice minister for public security.
Meng has lived in Lyon, where Interpol is headquartered, since assuming the role of president in 2016.
Meng was an active president. He sought to bring the 70-year-old agency into the 21st century, overseeing the development of clearer structures for cooperation and innovation.
Responding to a question about Meng Hongwei at a daily briefing, Lu said "relevant people should not attempt to make excuses for their corrupted and criminal acts" by "slandering" the government of President Xi Jinping, who has waged a wide-ranging and politically charged campaign against graft. And he had a hand in Chinese police operations that reached overseas, including Operation Fox Hunt, which sought to repatriate hundreds of former Chinese officials and businesspeople who had fled overseas and were suspected of corruption.
On the aforementioned date, Grace said, Meng had sent her a text message on WhatsApp, saying, "Wait for my call", followed by an emoji showing a knife four minutes later, according to The Guardian. The announcement said Meng was being investigated for accepting bribes and other crimes that were a result of his "willfulness".
The Interpol tweeted it received Meng's resignation from his post. Some of them might have been pursued by Chinese authorities under Meng's watch.
Interpol President Meng Hongwei has resigned, after being detained by Chinese authorities who accuse him of corruption.
From a Chinese government perspective, there are two likely reasons for this action.
"As long as I can't see my husband in front of me, speaking to me, I can't have any confidence", Grace Meng was quoted as saying by French TV stations and Sunday newspapers.
After days of concealing his fate from the global community, the public security ministry has revealed that the vice minister accepted bribes, providing no further details on the allegations or the conditions and location of Meng's apparent detention. If Meng himself wasn't involved in such activities, he would have known where the bodies were buried-figuratively and perhaps literally.
Foreign ministry spokesperson Lu Kang said Monday that China would continue to act as a "responsible power" that will "play its necessary role in worldwide affairs and multilateral organisations". But in China domestic security and the party come before all else and negative foreign press is unlikely to move the country's leadership.
In a statement Friday, the French Interior Ministry confirmed that it was looking into the situation and that a "suitable police mechanism" had been put in place to guarantee Grace Meng's safety.
Interpol has 192 member nations; the organization allows police agencies to collaborate and share resources through a network of national bureaus. "Under the terms of INTERPOL's Constitution and Internal regulations, the Senior Vice-President serving on INTERPOL's Executive Committee, Mr. Kim Jong Yang of South Korea, becomes the Acting President". For the most part, its budget has been dependent on donor money from member countries.
But Meng's contributions were scrubbed from the security ministry's website, including a speech at an Interpol ceremony for fallen officers in March in which he hailed the "real heroes". It made no mention of the former Interpol president's whereabouts or the Chinese investigation.
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