First, the team deleted three imprinting regions of the genome from haploid ESCs from one female parent, then injected them into eggs from another mother.
Healthy mice babies with two mothers and no father have been born. The offspring eventually grew into healthy adults and even had their own healthy children.
Just as impressively, the created mice were able to live to adulthood and have offspring of their own.
Some reptiles, amphibians and fish can reproduce with one parent of the same sex.
They were also able to create 12 live mice with two fathers, but those pups survived only two days, indicating there were greater challenges for successful reproduction using two male parents.
A team of researchers has produced viable offspring from same-sex pairs of mice, using a novel technology that involves stem cells altered to remove certain genes.
To produce their healthy bimaternal mice, Dr Zhou, co-senior author Dr Baoyang Hu, co-senior author Dr Wei Li, and their colleagues used haploid embryonic stem cells (ESCs), which contain half the normal number of chromosomes and DNA from only one parent and which the researchers believe were the key to their success'.
US, Russian astronauts safe after emergency landing
The last time Moscow's space program had a crewed launch failure was during the Soviet era in 1983, when a Soyuz booster exploded. Russian Federation stands to lose that monopoly with the arrival of SpaceX's Dragon and Boeing's Starliner crew capsules .
Study author Qi Zhou, a developmental biologist, said their findings showed "a new and clear way to produce offspring between same-sex mammals". "We found in this study that haploid ESCs were more similar to primordial germ cells, the precursors of eggs and sperm". For example, there is a need to identify problematic imprinted genes that are unique to each species and ongoing concerns for the offspring that don't survive or that experience severe abnormalities. They then edited the cells to remove parts of DNA that normally block reproduction using only male or female genes.
The mechanism controls the growth of young mammals through parts of genes called imprinted regions, which require DNA from both male and female parents for normal growth.
She told The Sun: "Animal mothers are subjected to surgical procedures in order to harvest their eggs and implant the engineered embryos, many pregnancies fail, and the animals who are born are commonly forced to live with unintended debilitating conditions, such as missing eyes or ears, skin ulcers, deformed body parts, deafness, seizures, and heart failure, to name just a few".
They survived only 48 hours after birth, despite a complicated process of gene manipulation meant to eliminate abnormalities resulting from the same-sex reproductive process.
He said, "To consider exploring similar technology for human application in the near future is implausible". "However, the generated mice still showed defective features, and the method itself is very impractical and hard to use", said Zhou.
Despite having success with mice, Li said the same technique can not easily be applied to other mammals - such as humans - since each species has a unique set of problematic imprinted genes, and identifying these takes time.
'We also revealed some of the most important imprinted regions that hinder the development of mice with same sex parents, which are also interesting for studying genomic imprinting and animal cloning'.
By all accounts, Sarah Radney was safe inside her grandparents' home when Hurricane Michael roared into southwest Georgia. The Gadsden County Sheriff's office reported four people killed, with one young girl killed in Georgia .
Kane said: 'It was a unusual one, we're not using to playing with no fans, it's hard without the atmosphere'. We were braver and more decisive. 'Now the players are more established and look comfortable.
Google's new Pixel phones mirror an industry trend toward lusher, bigger screens and add twists on the camera for better pictures. The Pixel phones could enable better photos, but that alone may not be enough to lure smartphone users on a significant scale.
The Brewers proved ready, as they handled the Cubs and sent their rival to the one-game Wild Card against the Rockies. Orlando Arcia and Keon Broxton (home run) all chipped in run-producing hits in the win.
With the series on the line, the Indians sent Mike Clevinger to the mound against Dallas Keuchel with the season on the line. The Braves haven't been able to score a single run through the first two games, much less register a win.
USA astronaut Nick Hague and Russian cosmonaut Aleksey Ovchinin were rescued without injuries in Kazakhstan. NASA later tweeted images of the two men embracing their families back in Baikonur.
Israel halts Gaza fuel deliveries as 7 Palestinians killed
In a statement, the army said troops "spotted a number of assailants who climbed the security fence in the southern Gaza Strip". In response, the IDF said, soldiers used riot dispersal means and live fire in accordance with standard operating procedures.
Canal Water on the Rise
However, more than ten countries, including Ireland, showed a lack of appetite for increasing the EU's climate target. He recommended that Vietnam shift into a low-carbon economy, with a focus on the development of renewable energies .
Pope Francis Accepts Cardinal Wuerl's Resignation
Pope Benedict elevated then-Archbishop Wuerl to the College of Cardinals in November 2010, shortly after Wuerl's 70th birthday. Francis has said the devil is ultimately behind sex abuse of children by priests and current divisions in the Church .
Spidey Gets a New Suit in New Spider-Man
The belt is a bit different and features additional black accents, and the gloves have received more changes than anything else. After spending some time in Europe, principal photography on Spider-Man: Far From Home picked up in New York City this week.
Jetliner lands in US after world's longest flight
Singapore Airlines has held the coveted title before with. wait for it, a non-stop service between Singapore and Newark. The marathon flight had no standard economy seats, only so-called "economy comfort" and business class.
This human-like robot can now perform parkour
Atlas also used computer vision technology to tell exactly where it is in space and plan where to land when it jumps. Boston Dynamics' robots are moving in the opposite direction, learning new things at a terrifying rate.
Police called on black man babysitting white kids
Parker and Mango told police Lewis is a family friend and their children are in his youth program, called " Inspired by Lewis ". The officer is seen in the second video questioning Lewis and the two children at his home.